Allergy to house dust mites and successful AIT – Discover the connection

Last updated: 16th June, 2016

House dust mite allergy is a common cause of allergic asthma and allergic rhinitis. More than 130 million people are affected globally and due to the burden of disease, Allergen immunotherapy (AIT) may be considered in patients with perennial allergic rhinitis.
 
A key factor to successful AIT in house dust mite allergy is identification of the relevant allergens. The most common specific proteins are Der p 1 and Der p 2.
 
However, cross-reaction is frequent intra-species (Der p 1/Der p 2 and Der f 1/Der f 2), inter-species (Der p 1/Der f 1 and Der p 2/Der f 2) and between different extracts (e.g. Der p 10/tropomyosin).
 
ImmunoCAP Allergen Components can help you differentiate between specific and cross-reactive sensitization with the following suggested test profile.

Click here to view the Phadia Discover the Connection Allergic Rhinitis Pocket Card

Click here to view the Phadia Discover the Connection House Dust Mites brochure

dustmites2

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

References:

European Academy of Allergy and Clinical Immunology; Global Atlas of Allergic Rhinitis and Chronic Rhinosinusitis, 2015.
de Benedictis FM, et al. Allergy. 2009;64:295–303.
Thomas WR. Human Vaccines & Immunotherapeutics. 2012;8(10):1469-78.
Bessot JC and Pauli G. Eur Ann Allergy Clin Immunol. 2011;43:141-56.

 

Molecular Allergology Newsletter Sign Up Form

 

Go BackGo Back
Top