Milestone KOS

Bone decalcification with the KOS – a user’s perspective

Last updated: 17th July, 2020

A state-of-the-art, multifunctional microwave system, the KOS is a rapid, icon driven, multifunctional  processor. The multitasking nature of the instrument can enhance and accelerate many of the typical applications encountered in the histology laboratory.

  • Decalcification – improve your turn around time for bone decalcification!
    Milestone KOS

        Milestone KOS

  • Special Stains
  • Antigen Retrieval
  • Fixation
  • Gross Hardening
  • Tissue Processing
  • Electron Microscopy model available

Felicity Lawrence (senior histology technician at CARF Histology, Institute of Health and Biomedical Innovation, Queensland University of Technology) shares her feedback on two years’ experience using the KOS for bone decalcification:

“The ability to rapidly decalcify bone without damaging the integrity and antigenicity of the sample has been welcomed by many of our research groups. 

Whilst traditional decalcification with 10% EDTA takes 6 months at RT (longer at 4oC) to fully decalcify sheep tibial samples, the KOS rapid decalcifier reduces this time frame to 2-3 months, permitting quicker experimental investigations with faster publication of results. 

Whilst ongoing studies are looking to further reduce this timeframe, the current saving of 3-4 months during a PhD or Masters program is priceless.  The ability to batch process samples has reduced reagent consumption and time demands, improving cost efficiencies in terms of consumable costs and staff availability. 

Consequently, interest in and usage of the rapid decalcifier by many research groups has increased dramatically this year.”

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