Devyser LynchFAP NGS

Last updated: 15th January, 2024

Products are for professional/laboratory use only.

Devyser LynchFAP1 is the first kit on the market to accurately assess all PMS2 variants!

First commercial kit to include a long-range PCR to unambiguously determine variants in all PMS2 exons.

Devyser LynchFAP is a targeted next-generation sequencing (NGS) assay for the analysis of genes associated with hereditary colon cancer syndromes. The assay enables analysis of sequence variants (SNVs, CNVs, and indels) in 10 selected genes implicated in Lynch syndrome, Familial Adenomatous Polyposis, and MUTYH-Associated Polyposis.

A long-range PCR is incorporated into the simplified workflow to accurately localise variants in all PMS2 exons, including challenging regions homologous to the PMS2CL pseudogene. Devyser LynchFAP NGS, together with its dedicated software, enables fast and intuitive results, including the evaluation of PMS2 gene conversion with PMS2CL.

Genes included:

MLH1 MSH2 MSH6 PMS2 EPCAM
APC MUTYH POLE POLD1 CTNNB1

Watch the webinar on-demand webinar and learn more about Devyser LynchFAP – Devyser I Webinar on Devyser LynchFAP

 

View the LynchFAP NGS Flyer

Download Here >

References

1 Devyser LynchFAP NGS is for research use only (RUO).



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