LGC SeraCare Human Plasma

Last updated: 02nd August, 2022

Products are for professional/laboratory use only.

LGC SeraCare offers a wide range of biological materials you need to achieve consistent product quality. SeraCon and Basematrix products are formulated from human plasma and processed to resemble a serum like state. These products are well suited for use as a negative diluent for the production of controls and calibrators.


Normal Human Plasma

SeraCon and BaseMatrix are both derived from normal human plasma, well suited for use as a negative diluent for the production of controls and calibrators, and possess the following characteristics.

 


 

Human Material

  • Manufactured from human plasma obtained from donation centres in the USA with full traceability. A cost-effective human serum substitute.

Viral Testes and Certified

  • Plasma has been tested and certified negative for anti-HIV-1/2, anti-HCV, HBsAg and HIV-1 RNA. Further certification available for anti-HBc, anti-HTLV-I/II, Syphilis, anti-HAV, anti-HBc, HCV RNA and HBV DNA can be provided.

Customizable

  • LCG SeraCare can satisfy specialized needs with custom materials processing.

 


Consistent lot-to-lot performance

  • Produced according to cGMPs in ISO 13485-certified facilities.

SeraCon and Basematrix products are both formulated from human plasma and processed to resemble a serum like state, however the processing differs slightly based on intended use of the material. Refer to Table 1: Diluent Reference Guide for details. SeraCon is recommended for use in serological assays. It is also preferred when the intended application requires a matrix that is either free of lipids or hormones. BaseMatrix is recommended for use in molecular-based assays as a negative diluent for control and calibrator formulations.

 


Definition of terms  

  • Debriniated: Removal of clotting factors to mimic a serum-like state.
  • Dialyzed: Adjustment to normal physiological serum profile via buffer exchange across membrane (retains large molecule proteins).
  • Delipidated: Removal of lipid components.
  • Charcoal Stripped: Removal of hormones.
  • 0.2 mm Filtered: Final product filtration.

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