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Roche – Digital LightCycler

Roche Digital LightCycler® PRO System
Semi-automated system for the detection and absolute quantification of nucleic acid target copy number during Polymerase Chain Reaction (PCR) based Nucleic Acid Testing (NAT).

Make the leap from idea to impact

It’s time for a leap forward in digital PCR technology. The Roche Digital LightCycler System is the digital PCR instrument of tomorrow. With a unique combination of 3 nanowell plate configurations, 6 advanced optical channels, and 5x concentrated DNA and RNA master mixes, it has the potential to help your lab to make the leap from publishing research to producing clinically viable assays.


Bespoke testing with 3 one-of-a-kind1-4 nanowell plates

The unique hexagonal-shaped nanowell partitions and the filling dye that validates partitioning gives the Digital LightCycler System the ability to handle a wide variety of extracted samples such as FFPET, cfDNA, Whole Blood, and more.

Through these partitions, target sequences are efficiently concentrated within isolated microreactors. This concentration effect reduces template competition, thereby enabling the detection of rare mutations and allowing for a higher tolerance to inhibitors present in a sample.

High Resolution

15μL, 100,000 partitions

Copy Number Variation

NIPT

Human Genetic Disease

Universal Plate

30μL, 28,000 partitions

Gene Expression

Transplant Rejection

High Sensitivity

45μL, 20,000 partitions

Cell-free DNA

Oncology

Rare Mutation Detection


View the Roche Digital LightCycler brochure

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Explore the Roche Digital LightCycler Workflow brochure

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Whitepaper: The principles and performance of the Digital LightCycler System in an External Evaluation Programme (EEP)

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Visit the Roche website

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References:

  1. https://www.qiagen.com/us/products/instruments-and-automation/pcr-instruments/qiacuity-digital-pcr-system/ (last accessed on 08/20/2022)
  2. https://www.bio-rad.com/en-us/life-science/digital-pcr/qx-one-droplet-digital-pcr-ddpcr-system (last accessed on 08/20/2022)
  3. https://www.stillatechnologies.com/6-color-dpcr/ (last accessed on 08/20/2022)
  4. https://www.thermofisher.com/order/catalog/product/4489084 (last accessed on 08/20/2022)

 

THESE PRODUCTS ARE NOT AVAILABLE FOR PURCHASE BY THE GENERAL PUBLIC.

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