HistoCyte ROS1 Analyte Controls

Last updated: 06th July, 2021

ROS1 is a receptor tyrosine kinase (RTK) encoded by the ROS1 gene. Genetic rearrangements can occur with many different partner genes.

More recently, the detection of ROS1 by IHC  on formalin-fixed, paraffin-embedded specimens, together with FISH for detection of translocations or fusions, is being implemented in routine use for diagnosis of non-small cell carcinoma of the lung.

The HistoCyte ROS1 control consists of two cell lines: one with a SLC34A2-ROS1 translocation and resulting fusion protein; the other has no translocation and therefore no ROS1 protein expressed.

Along with the ALK-Lung (EML4-ALK) Analyte Control and PD-L1 Analyte ControlDR, the ROS1 Analyte Control further adds to HistoCyte’s non-small cell lung carcinoma range of biomarker controls.

Abacus dx is the exclusive distributor for HistoCyte in Australia only.

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