Sebia CAPILLARYS 3 HbA1c

Last updated: 14th July, 2020

Abacus dx offers laboratories the best equilibrium for HbA1c measurement between accuracy, robustness and throughput.

Sebia has adapted high-resolution capillary electrophoresis technology on its CAPILLARYS 3 TERA instrument for an accurate HbA1c measurement at a very high speed.

From whole blood sampling in primary capped tubes to the final result, the CAPILLARYS 3 TERA instrument performs all sequences automatically.

The clear-cut and precise separation of the different haemoglobin fractions allows accurate HbA1c measurement with no altered results in the presence of frequent interferences:

  • Labile A1c
  • Carbamylated Hb,
  • Hb F
  • Hb S
  • Hb C
  • Hb D
  • Hb E

As well as the incidental detection of the common haemoglobin disorders (sickle cell, beta-thalassemia, etc.).


 

 

 

 

 

 

 

 

 

 


Using the IFCC reference method calculation formula HbA1c/(HbA1c+HbA0), developed for the worldwide assay standardization, the Sebia methodology ensures accurate and reliable results.

Test Principle

The CAPI 3 HbA1c assay is based on the principle of capillary electrophoresis in free solution. Haemoglobin fractions are separated in silica capillaries, by their electrophoretic mobility and electroosmotic flow at a high voltage in an alkaline buffer. Haemoglobin fractions are directly detected at an absorbance of 415 nm.

Performances

  • Throughput: from 70 tests/h for CAPILLARYS 3 TERA stand alone to 210 tests/h with CAPILLARYS 3 TERA MC configuration
  • Between-run CVs: <2%
  • Full traceability and positive sample ID for blood samples
  • Full traceability and reagent management through RFID tags
  • Color-coded backlit reagent containers
  • Cap piercing and tube mixing from primary tubes
  • Rapid validation through color-coded profiles using the 96 profile mosaic screen
  • Large autonomy:
  • Samples up to 600 tubes (with tube loader)
  • >5 hours HbA1c testing

Capillarys 3 Automation

Complete walk-away technology

  • Capillarys 3 Octa
  • Capillarys 3 Tera
  • Capillarys 3 Tera MC1
  • Capillarys 3 Tera MC2
  • Capillarys 3 Tera MC3

Automatic red cell haemolysate preparation
High analytical precision
NGSP/IFCC certified results


 

 

 

 

 

 

 

 

 


PHORESIS CORE Software:

  • Interpretation and results validation
  • Multi-criteria search function; including patient result history
  • SQL Client/Server database
    • Networking of all Sebia Instruments
      • within a laboratory
      • between distant sites
    • Decentralised validation

 


View more Information on Sebia Capillarys 3

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Abacus dx is the exclusive distributor of Sebia in Australia only.

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