ESR1 Mutations are the Leading Cause of Primary Treatment Resistance in HR+ mBC
ESR1 gene codes for estrogen receptor alpha (ERα), and mutations in its ligand-binding domain trigger constant activation of the receptor, leading to excessive downstream signalling.
TriLink’s CleanCap® AG (3′ OMe) CleanScript™ IVT Kit provides essential components for mRNA synthesis using co-transcriptional capping by in vitro transcription (IVT). The kit components are sufficient to run 25 x 100 µL or 125 x 20 µL reactions reactions following our recommended IVT protocol with co-transcriptional capping.
Abacus dx believes in resilience and supporting our community. This commitment is evident in our partnership with the Paraplegic Benefit Fund (PBF), which is dedicated to assisting individuals with spinal cord injuries.
We were honoured to host Darron Shields from PBF at our 2025 Leadership Forum, whose story exemplifies resilience and determination. After a life-changing cycling accident, he faced immense challenges but achieved remarkable feats, including competing in para-triathlons. His journey highlights the strength of mindset, management of expectations, and perseverance.
While the majority of epidemiological data pertaining to Coeliac Disease (CeD) has originated from Europe and other parts of the world with predominantly Caucasian populations, current evidence estimates that the global prevalence of CeD is 0.7%.1
To complete your multiplex assay solutions, complement your portfolio of Merck MILLIPLEX® multiplex kits, instruments, software, and service distributed by Abacus dx with BioTek® microplate washers.
Explore the advantages of adding these to your multiplex workflow below.
BioTek® Microplate Washers For 96-Well Biomagnetic Separation
The new BioTek Magnetic 96-well washer, complete with Touch Screen and Ultrasonic cleaning incorporates a state-of-the-art, high resolution LED backlit touch screen user interface for intuitive and flexible onboard instrument control of 96-well microplate washing.
In today’s high-stakes scientific environment, precision isn’t just a goal – it’s a necessity. Laboratories are under immense pressure to deliver accurate results while boosting efficiency.
Certest Immunodiagnostic is committed to providing a comprehensive portfolio of diagnostic reagents for detecting infectious diseases and different markers, covering different needs of formats, types of use, throughput, precision, and time from sample to result.
Strongyloides is the only worm that can persist in the gastrointestinal tract without symptoms for decades and is often underdiagnosed.